• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: FOX{D1,D2}.p2

Z-value: 1.655

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_21084077	3.071		APOB	apolipoprotein B (including Ag(x) antigen)
chr5_+_78568094	2.980
chr5_+_78567604	2.905	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr10_+_63478974	2.847		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr1_+_144149794	2.714	NM_006472	TXNIP	thioredoxin interacting protein
chr20_-_45410033	2.655		ZMYND8	zinc finger, MYND-type containing 8
chr7_+_106596641	2.559	NM_012257	HBP1	HMG-box transcription factor 1
chr2_-_21084911	2.333		APOB	apolipoprotein B (including Ag(x) antigen)
chr7_+_134483305	2.305	NM_018295	TMEM140	transmembrane protein 140
chr19_+_18357966	2.248	NM_004864	GDF15	growth differentiation factor 15
chr19_+_1158129	2.099		EFNA2	ephrin-A2
chr13_+_96672705	1.903		MBNL2	muscleblind-like 2 (Drosophila)
chr1_+_196392513	1.829	NM_133494	NEK7	NIMA (never in mitosis gene a)-related kinase 7
chr14_+_31868229	1.803	NM_004274	AKAP6	A kinase (PRKA) anchor protein 6
chr20_+_254205	1.792	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr5_+_90711887	1.739		LOC100129716	hypothetical LOC100129716
chr2_+_96845704	1.718	NM_017623 NM_199078	CNNM3	cyclin M3
chr6_+_64403631	1.705		PHF3	PHD finger protein 3
chr6_+_64403685	1.691		PHF3	PHD finger protein 3
chr1_-_177378801	1.676	NM_001136000 NM_001168239 NM_005158	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr6_+_64403936	1.665		PHF3	PHD finger protein 3
chr4_+_140806536	1.643		MGST2	microsomal glutathione S-transferase 2
chr6_+_64403668	1.577		PHF3	PHD finger protein 3
chr12_+_105220638	1.555	NM_152772	TCP11L2	t-complex 11 (mouse)-like 2
chr3_+_180348818	1.544	NM_006218	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr3_-_15814678	1.480	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr6_+_64414389	1.480	NM_015153	PHF3	PHD finger protein 3
chr20_+_2030527	1.458	NM_080836	STK35	serine/threonine kinase 35
chr10_+_111959978	1.439	NM_001008541	MXI1	MAX interactor 1
chr20_+_2031418	1.369		STK35	serine/threonine kinase 35
chr4_+_140806371	1.364	NM_002413	MGST2	microsomal glutathione S-transferase 2
chr16_-_46957284	1.285	NM_001006610	SIAH1	seven in absentia homolog 1 (Drosophila)
chr20_+_62357490	1.282	NM_001104925 NM_018257	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr2_+_86800940	1.271		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr17_+_69939130	1.259	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr6_+_17708483	1.251	NM_016255	FAM8A1	family with sequence similarity 8, member A1
chr3_+_23962518	1.234	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr16_-_46957254	1.233		SIAH1	seven in absentia homolog 1 (Drosophila)
chr3_-_71196696	1.231		FOXP1	forkhead box P1
chr7_+_91408086	1.231	NM_005751 NM_147185	AKAP9	A kinase (PRKA) anchor protein (yotiao) 9
chr2_+_86800898	1.229	NM_022780	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr20_+_21054623	1.227	NM_001163022 NM_001163023 NM_018474	PLK1S1	polo-like kinase 1 substrate 1
chr8_-_29263714	1.199	NM_001394	DUSP4	dual specificity phosphatase 4
chr15_+_22781292	1.196		PAR5	Prader-Willi/Angelman syndrome-5
chr2_+_44249487	1.180	NM_001033556 NM_001033557 NM_002706 NM_177968 NM_177969	PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr2_+_86801081	1.174		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr3_-_188935363	1.174	NM_001134738	BCL6	B-cell CLL/lymphoma 6
chr2_-_69033515	1.165	NM_182536	GKN2	gastrokine 2
chr17_+_57909979	1.148	NM_001112707 NM_006852	TLK2	tousled-like kinase 2
chr2_+_44249565	1.133		PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr5_+_149845503	1.125		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_+_33494745	1.108	NM_152493	ZNF362	zinc finger protein 362
chr3_-_71376919	1.105		FOXP1	forkhead box P1
chr3_+_23961739	1.098	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr20_-_42561725	1.072
chr6_+_112481970	1.044	NM_003880 NM_198239	WISP3	WNT1 inducible signaling pathway protein 3
chr6_+_12120709	1.043	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr10_+_31650069	1.025	NM_001128128 NM_001174094	ZEB1	zinc finger E-box binding homeobox 1
chr10_+_82163568	1.022		C10orf58	chromosome 10 open reading frame 58
chr11_-_10630408	1.016	NM_001098579	MRVI1	murine retrovirus integration site 1 homolog
chr14_+_22136968	1.014	NM_022060	ABHD4	abhydrolase domain containing 4
chr18_+_58533597	1.003	NM_194449	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1
chr6_-_159386007	0.995	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr15_-_75135496	0.979		TSPAN3	tetraspanin 3
chr10_+_63331018	0.978	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr10_-_44794146	0.968	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr6_+_139136349	0.962	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr11_+_20005704	0.951		NAV2	neuron navigator 2
chr8_+_100025806	0.948	NM_001142462 NM_053001	OSR2	odd-skipped related 2 (Drosophila)
chr6_+_134800533	0.939		LOC154092	hypothetical LOC154092
chr6_-_56824371	0.931		DST	dystonin
chr11_+_101723125	0.927		BIRC2	baculoviral IAP repeat containing 2
chr2_-_65447370	0.922	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr6_-_27988152	0.917	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr1_-_159459814	0.888		APOA2	apolipoprotein A-II
chr2_-_160181206	0.886	NM_013450	BAZ2B	bromodomain adjacent to zinc finger domain, 2B
chr2_+_65136989	0.877	NM_015147	CEP68	centrosomal protein 68kDa
chr9_+_132990760	0.874	NM_005085	NUP214	nucleoporin 214kDa
chr12_-_52281050	0.873	NM_001130059	ATF7	activating transcription factor 7
chr7_+_107171514	0.872	NM_024814	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr2_+_151974630	0.864	NM_001177663 NM_018151 NM_001177664	RIF1	RAP1 interacting factor homolog (yeast)
chr20_+_56397568	0.862	NM_001195677 NM_004738	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_+_24518398	0.854	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr15_+_97009194	0.852		IGF1R	insulin-like growth factor 1 receptor
chr2_+_149119029	0.842	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr2_-_162808123	0.836	NM_004460	FAP	fibroblast activation protein, alpha
chr2_-_65447267	0.833		SPRED2	sprouty-related, EVH1 domain containing 2
chr2_-_213724577	0.829	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr5_+_27508139	0.825		LOC643401	hypothetical protein LOC643401
chr6_-_33276131	0.821		RXRB	retinoid X receptor, beta
chr14_+_59785723	0.813		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr3_+_64645819	0.812		LOC100507098	hypothetical LOC100507098
chr8_-_86441115	0.811	NM_001164830	CA1	carbonic anhydrase I
chr1_+_24518501	0.806	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr21_+_29593607	0.796	NM_206866	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_-_42124587	0.795	NM_001136017 NM_001136126	CCND3	cyclin D3
chr5_+_65258316	0.795		ERBB2IP	erbb2 interacting protein
chr5_+_162865128	0.795	NM_013283	MAT2B	methionine adenosyltransferase II, beta
chr2_-_138975682	0.783
chr10_+_18729518	0.771	NM_201570	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr11_-_56846246	0.763		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr17_+_36642240	0.760	NM_031962	KRTAP9-9 KRTAP9-3	keratin associated protein 9-9 keratin associated protein 9-3
chr16_-_4836198	0.756		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr1_-_180624494	0.755		GLUL	glutamate-ammonia ligase
chr14_+_59785739	0.753		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr5_+_72287625	0.752
chr20_+_56904042	0.744		GNAS	GNAS complex locus
chr4_-_152368492	0.742		SH3D19	SH3 domain containing 19
chr6_-_33276347	0.742	NM_021976	RXRB	retinoid X receptor, beta
chr7_-_99536214	0.728	NM_182776	MCM7	minichromosome maintenance complex component 7
chr2_-_192419896	0.728		SDPR	serum deprivation response
chr21_+_29439768	0.726		C21orf7	chromosome 21 open reading frame 7
chr2_+_196230096	0.717	NM_020342	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr13_+_75232797	0.716	NM_015842	LMO7	LIM domain 7
chr3_+_23904086	0.710		UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr1_-_180624380	0.702		GLUL	glutamate-ammonia ligase
chr7_-_155129817	0.701
chr6_-_33276141	0.700		RXRB	retinoid X receptor, beta
chr16_-_3362283	0.691	NM_001190476	MTRNR2L4	MT-RNR2-like 4
chr6_+_155579788	0.691	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr14_+_23937766	0.690	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr5_+_72287630	0.688		FCHO2	FCH domain only 2
chr5_+_137701852	0.686		FAM53C	family with sequence similarity 53, member C
chr5_+_137701855	0.679		FAM53C	family with sequence similarity 53, member C
chr1_-_150564302	0.679	NM_002016	FLG	filaggrin
chr2_+_172658453	0.676	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr5_+_72287509	0.675	NM_001146032 NM_138782	FCHO2	FCH domain only 2
chr5_-_16561936	0.675	NM_019000	FAM134B	family with sequence similarity 134, member B
chr19_+_1157462	0.673		STK11	serine/threonine kinase 11
chr14_+_101346032	0.669		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr14_+_59786047	0.669		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_-_33705244	0.663	NM_003915	CPNE1	copine I
chr20_+_43943254	0.663	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr2_-_192420168	0.662	NM_004657	SDPR	serum deprivation response
chr2_-_189752575	0.654	NM_000393	COL5A2	collagen, type V, alpha 2
chr7_-_112366962	0.651	NM_152556	C7orf60	chromosome 7 open reading frame 60
chr1_-_159459999	0.645	NM_001643	APOA2	apolipoprotein A-II
chr14_+_101345878	0.645	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr1_+_225194582	0.643		ADCK3	aarF domain containing kinase 3
chr1_+_225194616	0.632		ADCK3	aarF domain containing kinase 3
chr8_-_28299850	0.630	NM_018660	ZNF395	zinc finger protein 395
chr1_+_87567164	0.627		LMO4	LIM domain only 4
chr17_+_64922420	0.625	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr16_+_73590419	0.619		ZNRF1	zinc and ring finger 1
chr4_+_124537334	0.617	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_+_225194560	0.616	NM_020247	ADCK3	aarF domain containing kinase 3
chr14_+_23654307	0.604	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr1_+_225194622	0.601		ADCK3	aarF domain containing kinase 3
chrX_+_146801355	0.599
chr1_+_150753601	0.594	NM_019060	CRCT1	cysteine-rich C-terminal 1
chr18_+_64616296	0.593	NM_024781	CCDC102B	coiled-coil domain containing 102B
chr2_+_68815416	0.592	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr10_-_21226536	0.589	NM_006393	NEBL	nebulette
chr3_+_115099007	0.585	NM_001172105	GRAMD1C	GRAM domain containing 1C
chr2_+_151974849	0.585	NM_001177665	RIF1	RAP1 interacting factor homolog (yeast)
chr2_+_196229715	0.582	NM_001127257	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr7_+_155129904	0.580		RBM33	RNA binding motif protein 33
chr2_-_128358903	0.577	NM_031445	AMMECR1L	AMME chromosomal region gene 1-like
chr6_-_42124361	0.576		CCND3	cyclin D3
chr11_-_5247948	0.576	NM_005330	HBE1	hemoglobin, epsilon 1
chr3_+_69895310	0.576	NM_001184967	MITF	microphthalmia-associated transcription factor
chr4_+_95595419	0.574		PDLIM5	PDZ and LIM domain 5
chr2_+_61258263	0.571		AHSA2	AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr2_+_170149092	0.571	NM_004792	PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr6_+_12398514	0.569	NM_001168319 NM_001955	EDN1	endothelin 1
chr8_+_70567581	0.564	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr17_-_36719030	0.562	NM_001146182	KRTAP16-1	keratin associated protein 16-1
chr2_+_201689174	0.556		CFLAR	CASP8 and FADD-like apoptosis regulator
chr2_-_101457596	0.556	NM_001145664	RFX8	regulatory factor X, 8
chr14_-_34414603	0.547	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr1_+_87567136	0.546		LMO4	LIM domain only 4
chr17_+_36665161	0.542	NM_030975	KRTAP9-9	keratin associated protein 9-9
chr19_-_42880184	0.541		ZNF607	zinc finger protein 607
chr12_+_100198026	0.540	NM_014503	UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)
chr2_+_198089036	0.539		MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr17_+_54652609	0.529	NM_001165993 NM_001165994 NM_182569	GDPD1	glycerophosphodiester phosphodiesterase domain containing 1
chr2_+_120487072	0.525	NM_001184937 NM_001184939 NM_020909	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chr8_+_70567634	0.525		SULF1	sulfatase 1
chr10_-_90601655	0.524	NM_144590	ANKRD22	ankyrin repeat domain 22
chr2_+_120487076	0.523	NM_001184938	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chrX_+_146801142	0.523	NM_001185075 NM_001185076 NM_001185081 NM_001185082 NM_002024	FMR1	fragile X mental retardation 1
chr21_+_29593098	0.522		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr17_+_38916895	0.521		DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr5_+_137701122	0.516	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr8_-_13018123	0.516	NM_001164271	DLC1	deleted in liver cancer 1
chr17_+_38916758	0.515	NM_004941	DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr21_+_29593088	0.514	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_+_146801236	0.511		FMR1	fragile X mental retardation 1
chr7_+_116238309	0.510		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr21_+_29592984	0.510		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr5_+_137701601	0.507	NM_016605	FAM53C	family with sequence similarity 53, member C
chr8_+_21833111	0.507	NM_015024	XPO7	exportin 7
chr20_-_1257809	0.507	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr6_-_50039776	0.507	NM_001037499	DEFB114	defensin, beta 114
chr1_+_87569959	0.505		LMO4	LIM domain only 4
chr11_-_46572160	0.500		AMBRA1	autophagy/beclin-1 regulator 1
chr6_-_33862690	0.499	NM_001143944	LEMD2	LEM domain containing 2
chr20_-_33783409	0.497		RBM39	RNA binding motif protein 39
chr2_-_177210904	0.496		LOC375295	hypothetical LOC375295
chr6_-_105734535	0.493	NM_022361	POPDC3	popeye domain containing 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.38	2.03e-02	GO:0048519	negative regulation of biological process
1.40	2.76e-02	GO:0048523	negative regulation of cellular process
1.79	2.88e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.66	2.89e-02	GO:0006351	transcription, DNA-dependent
1.61	3.96e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.33	1.23e-02	GO:0045095	keratin filament

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.30e-02	GO:0005515	protein binding
1.70	1.88e-02	GO:0043565	sequence-specific DNA binding
1.56	2.55e-02	GO:0001071	nucleic acid binding transcription factor activity
1.56	2.55e-02	GO:0003700	sequence-specific DNA binding transcription factor activity