Motif ID: FOX{D1,D2}.p2

Z-value: 1.655


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
FOXD1 2297 forkhead box D1
FOXD2 2306 forkhead box D2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD1chr5_-_727801070.665.4e-03Click!
FOXD2chr1_+_476742750.116.7e-01Click!


Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_21084077 3.071 APOB
apolipoprotein B (including Ag(x) antigen)
chr5_+_78568094 2.980


chr5_+_78567604 2.905 NM_152405
 JMY
junction mediating and regulatory protein, p53 cofactor
chr10_+_63478974 2.847 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_144149794 2.714 NM_006472
 TXNIP
thioredoxin interacting protein
chr20_-_45410033 2.655 ZMYND8
zinc finger, MYND-type containing 8
chr7_+_106596641 2.559 NM_012257
 HBP1
HMG-box transcription factor 1
chr2_-_21084911 2.333 APOB
apolipoprotein B (including Ag(x) antigen)
chr7_+_134483305 2.305 NM_018295
 TMEM140
transmembrane protein 140
chr19_+_18357966 2.248 NM_004864
 GDF15
growth differentiation factor 15
chr19_+_1158129 2.099 EFNA2
ephrin-A2
chr13_+_96672705 1.903 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_196392513 1.829 NM_133494
 NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr14_+_31868229 1.803 NM_004274
 AKAP6
A kinase (PRKA) anchor protein 6
chr20_+_254205 1.792 NM_006943
 SOX12
SRY (sex determining region Y)-box 12
chr5_+_90711887 1.739 LOC100129716
hypothetical LOC100129716
chr2_+_96845704 1.718 NM_017623
NM_199078
 CNNM3

cyclin M3

chr6_+_64403631 1.705 PHF3
PHD finger protein 3
chr6_+_64403685 1.691 PHF3
PHD finger protein 3
chr1_-_177378801 1.676 NM_001136000
NM_001168239
NM_005158
 ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.79 2.88e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.66 2.89e-02 GO:0006351 transcription, DNA-dependent
1.61 3.96e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.40 2.76e-02 GO:0048523 negative regulation of cellular process
1.38 2.03e-02 GO:0048519 negative regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.33 1.23e-02 GO:0045095 keratin filament

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.70 1.88e-02 GO:0043565 sequence-specific DNA binding
1.56 2.55e-02 GO:0001071 nucleic acid binding transcription factor activity
1.56 2.55e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.16 1.30e-02 GO:0005515 protein binding